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  • 產(chǎn)品名稱： Recombinant Human SIRT4 protein
  • 產(chǎn)品貨號(hào)： CSP00632
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 1800
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購
    概述（Summary）
    英文全稱
    Recombinant Human SIRT4 protein
    純度（Purity）
    >90% as determined by SDS-PAGE
    內(nèi)毒素（Endotoxin level）
    Please contact with the lab for this information.
    蛋白構(gòu)建（Construction）
    A DNA sequence encoding the human SIRT4 (Ser28-Cys314) was fused with His tag
    Accession #
    Q9Y6E7
    表達(dá)宿主（Host）
    E.coli
    種屬（Species）
    Homo sapiens (Human)
    預(yù)測分子量（Predicted Molecular Mass）
    33.05 kDa
    制劑（Formulation）
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式（Shipping）
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶（Reconstitution）
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景（Background）
    背景介紹
    Downregulation of SIRT4 significantly increased tumor proliferation, migration and invasion. Additionally, downregulation of SIRT4 decreased the chemosensitivity of CRC cells by inhibiting cell apoptosis. Thus, these results suggest that SIRT4 may be a promising therapeutic target in CRC. SIRT4 in the control of energy metabolism and meiotic apparatus during oocyte maturation and indicate that SIRT4 is an essential factor determining oocyte quality. SIRT4 ameliorates MI-R injury through regulating mitochondrial function and apoptosis, and suggest that manipulating SIRT4 may be of clinical benefit in MI-R injury.
    分子別名（Alternative Names）
    NAD-dependent protein lipoamidase sirtuin-4, mitochondrial,NAD-dependent ADP-ribosyltransferase sirtuin-4,NAD-dependent protein deacetylase sirtuin-4,Regulatory protein SIR2 homolog 4,SIR2-like protein 4.
    Note
    For research use only .